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D-chiro inositol, an important new supplement for fertility

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Date:  11/02/2025
Author:  LivBio Staff
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If you are trying to get pregnant, you may not know that your body’s sensitivity to insulin is a key factor in fertility. We explain the role of D-chiro inositol, a naturally-occurring form of sugar, in supporting fertility if you have low sensitivity to insulin. We also set out why you need a precise dose of this important new fertility supplement for a successful pregnancy, and where to get it.

What is the role of insulin in fertility?

It may not be widely understood, but insulin plays a key role in conception and pregnancy. Different hormones in your body control every step of an egg developing to maturity. Hormones also control ovulation, when your body releases a mature egg, ready to be fertilised.

Insulin is a hormone which you may know mainly as controlling the levels of sugar in your blood. But it also plays a major role in regulating the levels of hormones at each step of the process of maturing eggs and ovulation.

What is low insulin sensitivity?

Low insulin sensitivity is a common but neglected condition among women who are trying to get pregnant. Low insulin sensitivity, also known as insulin resistance, means the body doesn’t react as it should to insulin. This can lead to the body producing more insulin in order to compensate, because in effect the body needs more insulin to do the same job of controlling blood sugar levels.

The resulting high insulin levels can harm the ability of the ovaries to regularly release eggs (to ovulate), making it difficult to get pregnant. High insulin can also cause your ovaries to produce too much of the male hormone testosterone.

  • A significant proportion of women in the UK who are trying to get pregnant have low sensitivity to insulin.
  • A small of portion of these women are diagnosed as diabetic or pre-diabetic. For women with a diagnosis, doctors can prescribe a drug called metformin. Metformin improves the body’s sensitivity to insulin, and supports conception.
  • However, the majority of women with low insulin sensitivity are not diagnosed. They can have a reduced chance of pregnancy and live birth because of the body’s problems in controlling the vital hormones that lead to eggs maturing and being released for fertilisation.

What are inositols? How can they help?

Inositols are types of natural sugars that are made in the body and found in some foods. There are nine types of inositols and the two that are most important to fertility are Myo inositol and D-chiro inositol. These two natural sugars are promising new ingredients for fertility supplements.

Recent scientific studies have shown that Myo inositol and D-chiro inositol, given as a supplement in certain precise doses, can regulate hormones and insulin, which is essential for fertility.

Following this discovery, inositols were introduced in the early 2000s as an effective way to improve insulin sensitivity and increase the chances of pregnancy. They are as effective as metformin in supporting fertility, but have far fewer unpleasant side effects, such as sickness and diarrhoea.

How do inositols support conception?

After we eat, insulin signals to the body to take up sugar in the form of glucose from the blood to the body’s tissues to use as energy. But insulin doesn’t work without enough D-chiro inositol. The body produces more insulin to compensate, disrupting hormone levels and fertility.

A woman normally produces 300mg of D-chiro inositol in her body. If someone lacks D-chiro inositol, taking the right level of this sugar as a supplement can restore the natural balance of insulin and other hormones vital to fertility.

What is the right dose of inositols?

Several studies have established that in order to support fertility, it is important to take Myo inositol and D-chiro inositol together. Clinical studies have also shown the proportion of inositols that is most effective to improve the chance of pregnancy: 1,100mg of Myo inositol together with 300mg of D-chiro inositol daily.

  • In one study, women with subfertility as a result of polycystic ovary syndrome were treated with 1,100mg of Myo inositol and 300mg of D-chiro inositol a day for three months. They achieved significantly higher pregnancy rates than women who were treated with a lower proportion of D-chiro inositol compared to Myo inositol.
  • In a separate study, women with delayed menstrual cycles as a result of polycystic ovary syndrome were treated with 1,100mg of Myo inositol and 300mg of D-chiro inositol daily for six months.
  • The menstrual cycles of 85 percent of the women treated became regular, improving the chance of conception.

Can I get a supplement with the right dose of inositols?

Yes – Ovosicare is the first fertility supplement with the formula of 1,100mg of Myo inositol and 300mg of D-chiro inositol. 300mg of D-chiro inositol is the amount produced naturally in a healthy body, and in the studies described above successfully improved regular ovulation and fertility.

There are other inositol supplements that contain D-chiro inositol. However, they contain 30mg, which is less than one tenth of the amount that in clinical studies successfully supported fertility.

Ovosicare is a complete fertility supplement based on up-to-date science. In addition to 300mg of D-chiro inositol, it provides you with the clinically recommended dose of:

  • 1,100 mg Myo-inositol, which also plays an important role in improving the body’s sensitivity to insulin, the healthy function of the ovaries and the development of eggs.
  • A bioactive form of folic acid called Quatrefolic®, which is easily absorbed and which helps cell development.
  • Pomanox®, an extract of fresh pomegranate, which is a powerful antioxidant – important to improve the quality of cells in the ovaries.
  • Vitamins B1, 2, 3, 6, 12, D, E, Zinc, Iodine, and Selenium, that are vital for a baby’s development and growth.

Where can I get Ovosicare?

Ovosicare is the top selling pregnancy supplement in Spain and France and is now available in the UK through Livbio.

Since its launch in 2020, 170,000 women internationally have chosen Ovosicare® Fertility to boost their chances of pregnancy. All its ingredients are from natural sources.

The recommendation is to start Ovosicare as soon as you decide to become pregnant. To find out more and to buy this unique fertility supplement, visit Ovosicare | LivBio

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