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Papilocare 21 is the world’s first natural treatment to prevent and heal cervical lesions caused by the human papillomavirus (HPV). It is a vaginal gel to be used on the mucous membranes of the vagina.

Papilocare is proven to effectively treat low-grade (CIN1) HPV-related cervical lesions after 6 months when used as recommended. You can expect to see results from 3 months onwards. It also improves the chance of clearing HPV virus regardless of the strain after a 6 months treatment.

For dosing and recommendations on how much product you need, see ‘How to use’ below.

Papilocare® contains the following natural ingredients:

  • Coriolus versicolor: stimulates the immune response
  • Neem (azadirachta indica): repairs tissues
  • Aloe vera: repairs tissues
  • Centella asiatica: repairs tissues
  • Bioecolia: promotes a healthy microbiota
  • Hyaluronic acid: moisturises tissues
  • Beta-glucan: has an anti-inflammatory and anti-oxidant effect

Papilocare® is paraben-free. It contains lactic acid.

Learn more about natural ingredients for women’s health

Research shows that Papilocare® can repair HPV-related lesions 6 months after using the gel as recommended.

In the PALOMA study the percentage of patients who had normal cervical smear test findings (also called a pap smear or pap test) was significantly higher in the group of women who were treated with Papilocare® than in the control group, who did not receive the treatment.

Read the Papilocare research in full

Here’s how much product you need:

If you have periods

For the first month:

  • Use one application every day, skipping the treatment during menstruation. On
    average you will need 21 tubes (cannulas) for the first month.

From month 2 to month 6:

  • Use one application every other day, skipping the treatment during menstruation. On
    average you will need 50-60 tubes for months 2 to 6 (10-12 tubes per month x 5
    months).

In total, 71-81 tubes are needed for the six months treatment.
LivBio offers an economical six month treatment package of 84 cannulas (4 boxes of 21 cannula format).

If you do not have periods
For the first 21 days:

  • Use one application every day for the first 21 days.

For the next 4 months:

  • Use one application every other day.
  • In total, around 75 tubes (cannulas) are needed.

LivBio offers an economical full treatment package of 84 cannulas (4 boxes of 21 cannula format).

You can use Papilocare® at any time of day, but the gel is more likely to remain in place if you apply it just before bedtime.
Pause the treatment during menstruation.

  1. Lie down, remove the cap from the nozzle of the tube containing the gel. Gently insert the nozzle completely into the vagina. Do not use if the tube is open or appears broken.
  2. If you find it helpful, you can squeeze out a small quantity of the gel and rub it around the tip of the tube to lubricate it.
  3. Squeeze the container (from the bottom to the top) until it is empty, then gently remove the nozzle from the vagina while still squeezing the tube, to avoid gel being sucked back into the container.
  4. Do not rinse.
  5. Discard the single-dose tube.

Sometimes a small amount of the gel will remain in the tube after use. However, it does not mean that you did not release a sufficient dose. 3ml of the gel is sufficient to cover the cervical-vaginal mucosa while each tube contains 5ml. Please do not reuse any gel that remains in the tube.

Papilocare® Vaginal Gel

Papilocare®  is the world’s first natural treatment to prevent and heal cervical lesions caused by the human papilloma virus (HPV). Papilocare®  is proven to effectively treat HPV-related cervical lesions and clear all HPV strains after 6 months, when used as recommended. You can expect to see results from 3 months onwards.

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£21.70£200.80 (VAT included)

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Frequently asked questions

Papilocare® is a natural vaginal gel treatment for women with HPV. It will treat cervical lesions, or, if you haven’t yet developed lesions, it will prevent them, and help speed up the eradication of the virus. This HPV natural treatment has been used by over 500,000 women in Europe and America since 2016, and is now available in the UK and Ireland.
Here’s how much product you need: If you have periods For the first month: Use one application every day, skipping the treatment during menstruation. On average you will need 21 tubes (cannulas) for the first month. From month 2 to month 6: Use one application every other day, skipping the treatment during menstruation. On average you will need 50-60 tubes for months 2 to 6 (10-12 tubes per month x 5 months). In total, 71-81 tubes are needed for the six months treatment. LivBio offers an economical six month treatment package of 84 cannulas (4 boxes of 21 cannula format). If you do not have periods For the first 21 days: Use one application every day for the first 21 days. For the next 4 months: Use one application every other day. In total, around 75 tubes (cannulas) are needed. LivBio offers an economical full treatment package of 84 cannulas (4 boxes of 21 cannula format). You can use Papilocare® at any time of day, but the gel is more likely to remain in place if you apply it just before bedtime. Pause the treatment during menstruation. Lie down, remove the cap from the nozzle of the tube containing the gel. Gently insert the nozzle completely into the vagina. Do not use if the tube is open or appears broken. If you find it helpful, you can squeeze out a small quantity of the gel and rub it around the tip of the tube to lubricate it. Squeeze the container (from the bottom to the top) until it is empty, then gently remove the nozzle from the vagina while still squeezing the tube, to avoid gel being sucked back into the container. Do not rinse. Discard the single-dose tube. Sometimes a small amount of the gel will remain in the tube after use. However, it does not mean that you did not release a sufficient dose. 3ml of the gel is sufficient to cover the cervical-vaginal mucosa while each tube contains 5ml. Please do not reuse any gel that remains in the tube.
We recommend Papilocare is used for 6 months per manufacturer advice, before re-evaluating. This advice is based on the most comprehensive clinical data, a research study in which patients were treated with Papilocare® for 6 months. However, you can consult your doctor about the dosage and duration of treatment that’s best for you.
Papilocare® works by: Restoring the lining of the cervix Rebalancing the natural protective environment of the vagina (the vaginal microbiota) Boosting the body’s local immune response to the virus. The effect is to help speed up the rate that HPV is cleared from the body, and repair cervical lesions, or prevent them from developing.
Papilocare® contains the following natural ingredients: Coriolus versicolor: stimulates the immune response Neem (azadirachta indica): repairs tissues Aloe vera: repairs tissues Centella asiatica: repairs tissues Bioecolia: promotes a healthy microbiota Hyaluronic acid: moisturises tissues Beta-glucan: has an anti-inflammatory and anti-oxidant effect Papilocare® is paraben-free. It contains lactic acid. Learn more about natural ingredients for women’s health
Research shows that Papilocare® can repair HPV-related lesions 6 months of using the gel as recommended. In the PALOMA study the percentage of patients who had normal cervical smear test findings (also called a pap smear or pap test) was significantly higher in the group of women who were treated with Papilocare® than in the control group, who did not receive the treatment. Read the Papilocare research in full
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Papilocare has been used by over 600,000 women since its launch in 2016. It is considered to be generally safe. The rare side effect is sensation of irritation at the beginning of treatment. This is considered to come from the pH level of the product (5.5) which is the normal pH level of healthy vagina; however, some women have higher pH level, causing feeling of burning when the gel is applied due to incompatible pH levels. The irritation normally disappears after a few days. The manufacturer recommends that you interrupt the treatment until the irritation disappears. If the condition persists, you should stop using the product.
There is no clinical data available with this patient population. If you are trying to get pregnant, a doctor should be consulted prior to consideration of using the product.
Although Papilocare is not contraindicated in pregnancy or breastfeeding, there is no clinical data available with these patient population. In case of pregnancy or breastfeeding, a doctor should be consulted prior to consideration of using the product.
If you are wearing vaginal contraceptives, Papilocare vaginal gel’s manufacturer recommends that you do not use Papilocare. There is no clinical data in this population.
Papilocare is compatible with natural latex rubber condoms.

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Disclaimer: Information on this website is provided for informational purposes only and not intended as a substitute for the advice provided by your physician or other healthcare professional. You should not use the information on this website for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment. For medical advice, diagnosis and prescription, please consult a healthcare professional.

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