Papilocare 21 is the world’s first natural treatment to prevent and heal cervical lesions caused by the human papillomavirus (HPV). It is a vaginal gel to be used on the mucous membranes of the vagina.

Papilocare is proven to effectively treat HPV-related grade cervical lesions and clear all HPV strains after 6 months when used as recommended. You can expect to see results from 3 months onwards.

For dosing and recommendations on how much product you need, see ‘How to use’ below.

Starter pack available – Click Here

For more information on HPV and persistent HPV, visit Jo’s Cervical Cancer Trust.

Papilocare® is a natural vaginal gel treatment for women with HPV. It will treat cervical lesions, or, if you haven’t yet developed lesions, it will prevent them, and speed up the eradication of the virus.

This HPV natural treatment has been used by over 50,000 women in Europe and America since 2016, and is now available in the UK and Ireland.

Here’s how much product you need:

If you have periods

For the first month:

• Use one application every day, skipping the treatment during menstruation. On
  average you will need 21 tubes (cannulas) for the first month.

From month 2 to month 6:

• Use one application every other day, skipping the treatment during menstruation. On
  average you will need 50-60 tubes for months 2 to 6 (10-12 tubes per month x 5
  months).

In total, 71-81 tubes are needed for the six months treatment.
LivBio offers an economical six month treatment package of 84 cannulas (4 boxes of 21 cannula format).

If you do not have periods
For the first month:

• Use one application every day for the first 21 days.

For the next 126 days:

• Use one application every other day for another 126 days (63 tubes). You will complete the treatment in around 147 days (or approximately 5 months).
• In total, 84 tubes (cannulas) are needed.

LivBio offers an economical full treatment package of 84 cannulas (4 boxes of 21 cannula format).

You can use Papilocare® at any time of day, but the gel is more likely to remain in place if you apply it just before bedtime.
Pause the treatment during menstruation.

1. Lie down, remove the cap from the nozzle of the tube containing the gel. Gently insert the nozzle completely into the vagina. Do not use if the tube is open or appears broken.
2. If you find it helpful, you can squeeze out a small quantity of the gel and rub it around the tip of the tube to lubricate it.
3. Squeeze the container (from the bottom to the top) until it is empty, then gently remove the nozzle from the vagina while still squeezing the tube, to avoid gel being sucked back into the container.
4. Do not rinse.
5. Discard the single-dose tube.

Sometimes a small amount of the gel will remain in the tube after use. However, it does not mean that you did not release a sufficient dose. 3ml of the gel is sufficient to cover the cervical-vaginal mucosa while each tube contains 5ml. Please do not reuse any gel that remains in the tube.

We recommend Papilocare is used for 6 months per manufacturer advice, before re-evaluating. This advice is based on the most comprehensive clinical data, a research study in which patients were treated with Papilocare® for 6 months. However, you can consult your doctor about the dosage and duration of treatment that’s best for you.

Papilocare® works by:

• restoring the lining of the cervix
• rebalancing the natural protective environment of the vagina (the vaginal microbiota)
• boosting the body’s local immune response to the virus.

The effect is to speed up the rate that HPV is cleared from the body, and repair cervical lesions, or prevent them from developing.

Papilocare® contains the following natural ingredients:

• Coriolus versicolor: stimulates the immune response
• Neem (azadirachta indica): repairs tissues
• Aloe vera: repairs tissues
• Centella asiatica: repairs tissues
• Bioecolia: promotes a healthy microbiota
• Hyaluronic acid: moisturises tissues
• Beta-glucan: anti-inflammatory and anti-oxidant

Papilocare® is paraben-free. It contains lactic acid.

Learn more about natural ingredients for women’s health

Research shows that Papilocare® can repair HPV-related lesions after three months, and can clear the virus after 6 months of using the gel as recommended.

In the PALOMA study the percentage of patients who had normal cervical smear test findings (also called a pap smear or pap test) was significantly higher in the group of women who were treated with Papilocare® than in the control group, who did not receive the treatment.

Read the Papilocare research in full

Papilocare® has not been tested with pregnant women. Although there is no evidence to show that the use of Papilocare® during pregnancy causes issues, we recommend that you consult your doctor before using the product.

Some women may experience irritation, itching and/or a burning sensation after using Papilocare®. This type of reaction is more common in women with a very sensitive or significantly damaged genital area or with an altered vaginal pH (for example, women who are post-menopausal, or have had a recent vaginal infection). One possible cause of irritation is the difference between the alkaline vaginal pH of peri- or post-menopausal women and the pH of the product, which is 5.5. Another possible reason is an allergy to any of the ingredients. Papilocare® contains lactic acid and so if you are allergic to it, you should not use the product.

Some women find these side effects disappear as they continue to use Papilocare®. If you find the side effects are severe or persistent, stop using the product and consult your doctor.

Papilocare® hasn’t been tested on women who are pregnant or breastfeeding. Consult your doctor before starting a course of Papilocare® if you are pregnant or breastfeeding.